Upper Respiratory Infection, Pertussis (Whooping Cough)
Автор: Aled Roberts
Загружено: 2026-02-03
Просмотров: 0
Описание: In this video, pertussis (whooping cough) is examined as an infection that begins in the upper respiratory tract and can progress to involve the lower airways. The video describes transmission via respiratory droplets, colonisation of the ciliated epithelium by Bordetella pertussis, and the relatively long incubation period associated with this infection. It explains how disease pathology is driven primarily by toxin production rather than bacterial invasion, focusing on pertussis toxin, which disrupts immune cell signalling and delays clearance, and tracheal cytotoxin, which paralyses cilia and impairs mucociliary clearance. The role of adhesins in maintaining attachment to epithelial cells is outlined, alongside the characteristic three-stage clinical course of disease. Finally, the video covers antibiotic treatment, the importance of early intervention, and vaccination using pertussis toxoid and adhesion antigens to reduce disease incidence.
Повторяем попытку...
Доступные форматы для скачивания:
Скачать видео
-
Информация по загрузке: