Tedizolid; Chemical name, Molecular Formula, Molar mass, Chemical Structure
Автор: Sokoto Pharmacology
Загружено: 2026-02-16
Просмотров: 4
Описание:
Chemical Details
Chemical name (IUPAC):
(5R)-3-
\[(2-methyl-1H-pyrazol-5-yl)methyl]-2-oxo-1,3-oxazolidine-5-carboxamide
Molecular formula:
C₁₇H₁₅FN₆O₃
Molar mass:
≈ 370.34 g/mol
Chemical structure (description):
Tedizolid is an oxazolidinone-class antibiotic, structurally related to linezolid but with modifications that enhance potency:
A five-membered oxazolidinone ring (the pharmacophore of this antibiotic class).
A carboxamide substituent at position 5, important for ribosomal binding.
A pyrazole ring attached via a methyl linker, which increases antibacterial activity.
A fluorine atom on the aromatic ring, improving lipophilicity and potency.
Multiple nitrogen atoms in heterocycles, contributing to hydrogen bonding and target specificity.
Several stereocenters, giving it a defined 3D conformation crucial for binding to the bacterial 50S ribosomal subunit
#Tedizolid
Повторяем попытку...
Доступные форматы для скачивания:
Скачать видео
-
Информация по загрузке:
