Sleep 8.2 | The Suprachiasmatic Nucleus: The Body’s Central Clock
Автор: Labfront
Загружено: 2025-11-20
Просмотров: 56
Описание:
Discover how the suprachiasmatic nucleus (SCN) keeps your body on time. This video dives into the SCN’s structure, light sensitivity, and its role in synchronizing biological rhythms. Explore how melanopsin-containing retinal cells detect light, the transcription–translation feedback loop (TTFL), and the effects of artificial lighting on circadian health. We also cover the phase response curve and its clinical relevance for sleep, jet lag, and shift work.
00:00 Introduction to the Suprachiasmatic Nucleus (SCN)
01:36 SCN Synchronization Mechanisms
02:38 Intrinsic Circadian Rhythms
03:55 Role of Light in Circadian Rhythms
05:04 Impact of Modern Lighting on Circadian Rhythms
06:02 Melatonin Suppression by Light
07:50 Molecular Mechanisms of Circadian Rhythms
09:11 Phase Response Curve and Clinical Relevance
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