Tobramycin; Chemical name, Molecular Formula, Molar mass, Chemical Structure
Автор: Sokoto Pharmacology
Загружено: 2026-02-16
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Описание:
🔬 Chemical Details
Chemical name (IUPAC):
(2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran
Molecular formula:
C₁₈H₃₇N₅O₉
Molar mass:
≈ 467.52 g/mol
Chemical structure (description):
Tobramycin is an aminoglycoside antibiotic. Its structure includes:
A central 2-deoxystreptamine ring.
Two attached amino sugars (nebrosamine and garosamine), which are critical for antibacterial activity.
Multiple hydroxyl groups and amino substituents, giving it high polarity and water solubility.
Several stereocenters, ensuring a rigid 3D conformation for ribosomal binding.
This configuration allows Tobramycin to bind to the 30S ribosomal subunit, interfering with protein synthesis and causing bacterial cell death
#Tobramycin
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