Cephalosporins: Pharmacology and How they Work for Medical Professionals

Описание: In this video, you will learn about how cephalosporins work and what they cover. Don't forget to LIKE & SUBSCRIBE!

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Time Stamps:
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00:00 Start
00:24 Cephalosporins Mechanism of Action
02:36 Cephalosporins Mechanism of Resistance
03:50 1st generation Cephalosporins (Cefazolin/Cephalexin)
05:25 2nd generation Cephalosporins (Cefixime, Cefdinir, Cefotetan, Cefoxitin)
07:07 3rd generation Cephalosporins (Ceftriaxone)
09:59 4th generation Cephalosporins (Cefepime)
10:48 5th generation Cephalosporins (Ceftaroline)
13:41 Special Cephalosporin Combos (Ceftolozane-tazobactam [Zerbaxa] and Ceftazidime-avibactam [Avycaz])

The following abbreviations were used in this video:
GNB Gram Negative Bacteria
-CXT: Ceftriaxone
-PCN: Penicillin
-MSSA: methicillin sensitive staphylococcus aureus
-MRSA: methicillin resistant staphylococcus aureus
-CRE: carbapenem resistant enterobacteriaceae
-pts: patients
-CNS: central nervous system
-VISA: vancomycin intermediate staphylococcus aureus
-B. fragilis: Bacteroides fragilis
-MDR: multi-drug resistant
-IV: intravenous
-PO: oral
-mg: milligrams

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📚 References:
❇️ van Duin D, Bonomo RA. Ceftazidime/Avibactam and Ceftolozane/Tazobactam: Second-generation β-Lactam/β-Lactamase Inhibitor Combinations. Clin Infect Dis. 2016;63(2):234-241. doi:10.1093/cid/ciw243 https://www.ncbi.nlm.nih.gov/pmc/arti...
❇️ Queenan AM, Bush K. Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev. 2007;20(3):440-458. doi:10.1128/CMR.00001-07 https://www.ncbi.nlm.nih.gov/pmc/arti...
❇️ Stapleton PD, Taylor PW. Methicillin resistance in Staphylococcus aureus: mechanisms and modulation. Sci Prog. 2002;85(Pt 1):57-72. doi:10.3184/003685002783238870 https://www.ncbi.nlm.nih.gov/pmc/arti...
❇️ Cunha, C. A., & Cunha, B. A. (2017). Antibiotic essentials (15th ed.). New Delhi, India: Jaypee Brothers Medical Publisher.;

📷 References:
https://www.latimes.com/recipe/proofs...
https://www.medicalnewstoday.com/arti...
https://www.verywellhealth.com/staph-...
https://www.cdc.gov/antibiotic-use/co...
https://www.med-ed.virginia.edu/cours...
https://www.sepsis.org/sepsisand/meni...
https://www.pngguru.com/free-transpar...
https://www.cdc.gov/hai/organisms/pse...
https://www.jungleroots.com/post/what...
https://www.mims.com/malaysia/drug/in...
https://www.empr.com/drug/avycaz/
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