🌪️ The Salicylate Spiral: When Aspirin Turns Acidic
Автор: medschoolbro
Загружено: 2025-06-23
Просмотров: 9107
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⏱️ Timeline:
• Early toxicity → Respiratory alkalosis
• Late toxicity → High anion gap metabolic acidosis
• Classic = Mixed disorder (↑ pH, ↓ CO₂, ↓ HCO₃⁻)
❌ Pro Tip: Don’t intubate unless you can match their hyperventilation — or you’ll trap CO₂ and tank the pH.
💉 Treatment:
• Activated charcoal (if early + alert)
• IV sodium bicarb to alkalinize urine & serum
• Hemodialysis if severe or deteriorating
❓What’s the first-line treatment for moderate salicylate toxicity?
A. Sodium bicarbonate
B. Hemodialysis
C. Acetylcysteine
D. Intubation with mechanical ventilation
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