The Orexin Hormone | What Does Orexin Do In Sleep?

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TIMELINE:

00:00 Introduction
00:51 Are you struggling with sleep?
01:36 Orexin controls sleep/wake cycles
03:28 Orexin controls your appetite
04:21 Orexin and energy balance and dopamine
05:03 The effect of orexin on brain health
05:48 The effects of fasting on the wake-promoting neurotransmitter orexin-A
07:59 The fasted snack
09:21 Improve orexin with foods

REFERENCE:

The effects of diurnal intermittent fasting on the wake-promoting neurotransmitter orexin-A

Food restriction has been demonstrated to increase the alertness in different species and to increase the levels of the wake-promoting neurotransmitter orexin. We hypothesized that diurnal intermittent fasting (DIF) increases orexin-A levels during fasting. Therefore, we conducted this study to assess the effects of DIF, during the month of Ramadan, on orexin, while controlling for lifestyle changes that may accompany Ramadan such as sleep duration, bedtime and wake time, energy expenditure, light exposure, and food.

https://pubmed.ncbi.nlm.nih.gov/29387256

Your Diet Can Boost Brain Function: The Link Between Orexin Cells And Food Decoded

Role Of Diet In Keeping Orexin Cells Active

The intensity of orexin cells signals can be tuned or influenced by diet. Orexin cells are uniquely sensitive to changes in the body's levels of certain dietary macronutrients, such as sugar and some amino acids. The potent inhibitor for orexin cells is glucose. When the level of glucose rises in the body, the cells stop generating their wake-promoting signals. In contrast, dietary non-essential amino acids i.e., those that our bodies can make are potent stimulators of orexin cells. Most foods containing proteins, such as eggs or tofu, are also responsible in keeping these cells alert.

That is how; if our orexin cells are provided enough stimulants to stay awake, our brain will also be awake. Experts also say that people who do not consume enough food might suffer from conditions like narcolepsy.

https://www.thehealthsite.com/disease...

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