Consequences of Deficient Sleep

Описание: This clip, from NEI's Stahl's Essential Videos, discusses how disturbances in the sleep/wake cycle can have profound influences on both physical and mental health. Access the full video collection here https://nei.global/epvideo

From a neuropathological perspective, disruption in sleep may affect synaptic potentiation and/or synaptic pruning. Chronically disturbed sleep can increase the risk of mental illness, cardiometabolic disorders, and cancer, as well as disrupt immune and endocrine function.

Disturbances in the sleep/wake cycle has been shown to impair hippocampal neurogenesis, which may partially explain the profound effects of sleep deprivation on cognitive functioning, including impairments in attention, memory deficits, and an inability to process new information.

Disturbances in the sleep/wake cycle can decrease circulating levels of the appetite-inhibiting hormone leptin and increase circulating levels of the appetite-stimulating hormone ghrelin, as well as contribute to gut microbiota dysbiosis. These changes may lead to increased risk of obesity, type 2 diabetes, and cardiovascular disease.

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