Symptoms to Circuits in Mood Disorders

Описание: This clip, from NEI's Stahl's Essential Videos, covers how the symptoms of mood disorders can be mapped onto brain circuits. Access the full video collection here: https://nei.global/epvideo

Each of the nine symptoms listed for the diagnosis of a major depressive episode can be mapped onto brain circuits whose inefficient information processing theoretically mediates these symptoms. Each of the symptoms listed for the diagnosis of a manic episode can similarly be mapped onto some of these same but also some different brain circuits. Each node in the networks regulating psychiatric symptoms has neurotransmitters distributed to it in a unique if partially overlapping pattern that regulates each specific hypothetically malfunctioning brain region. Targeting each region with drugs that act on the relevant neurotransmitters that regulate those brain regions potentially leads to reduction of each individual symptom.

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