Cystic Fibrosis Explained | Why CFTR Channel Is So Unique? | MBBS | NEET PG | Dr Vivek Nalgirkar |

Описание: Cystic fibrosis is a genetic disorder caused by a defect in a very unusual ion channel — the CFTR channel.

What makes this channel special?
👉 It is named after the disease itself
👉 It functions as a chloride (Cl⁻) channel
👉 It also regulates and inhibits other adjacent ion channels

Pathophysiology of cystic fibrosis involves a channel.
It is a Cl- channel. The channel is named after the disease, which is unusual.
It regulates not only the flow of Cl- through it, but also regulates/inhibits flow of other ions through other adjacent channels.
Watch the video to understand its pathophysiology in detail.

In this concept-based video, we explain the pathophysiology of cystic fibrosis in a clear, exam-oriented manner — focusing on how CFTR dysfunction leads to thick secretions, recurrent infections, and multisystem involvement.

🧠 In this video, you will understand:

• What is the CFTR channel and why it is unique
• How CFTR regulates chloride movement
• How it indirectly controls sodium and water transport
• Why its dysfunction causes thick mucus
• The integrated physiology behind cystic fibrosis

🎯 High-yield for:

• 1st MBBS – Physiology
• Pathophysiology concepts
• NEET PG / NExT / FMGE
• USMLE / PLAB basics
• Channelopathies & transport mechanisms

📌 Language: English (conceptual)
📌 Topic: Physiology – Cell membrane & ion channels

👉 Watch till the end — CFTR is a favorite examiner concept and easy to score when understood properly.

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