3 IVF Failures Despite Good Embryos: The Hidden Cause! | Fertility Class #3 | Dr Jay Mehta

Описание: Failed IVF cycles can be emotionally and physically challenging. When euploid embryos fail to implant or result in miscarriage, it is essential to evaluate beyond routine tests.

One of the common but often overlooked causes is chronic endometritis. This condition can be diagnosed through an endometrial biopsy and, if confirmed, treated with a specific course of antibiotics to improve endometrial receptivity.

Immunological evaluation is also important in such cases. However, a positive ANA titer alone does not justify immunotherapy like LIT. A complete immunological workup including APLA, anticardiolipin antibodies, thyroid profile, and CDC crossmatch helps guide appropriate treatment.

In selected patients with repeated failure despite euploid embryo transfer, immunomodulatory therapy using medications like prednisolone, hydroxychloroquine, or tacrolimus may be considered. These should always be prescribed under expert guidance, preferably with input from transplant or immunology specialists.

Every case of recurrent IVF failure requires an individualized, evidence-based approach. Proper diagnosis and timely intervention can significantly improve outcomes.

If you are struggling with repeated IVF failures or need a second opinion, consult an experienced fertility specialist.

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