PNS Pharmacology | Astringents |DRUGS INHIBITING AFFERENT INNERVATION

Описание: Astringents are the agents that precipitate protein and form albuminates on
the surface of the damaged skin or the mucous membrane, thus protecting the
receptors from irritating factors and relieving pain.

CLASSIFICATION
Organic substances
– Tannin
– Tanalbinum
– herb of Saint-John’s-wort (herba Hyperici)
– flowers of chamomile (flos Chamommillae)
– leaves of salvia (folium Salviae)
– bark of oak (Cortex Quercus)
Non-organic substances
– Bismuth subnitrate.

Peculiarities of preparations:-

Tannin is an organic astringent; is used in the form of solution, ointment, powder
for external use; has astringent and anti-toxic action (is an antidote in poisonings

Tanalbinum is a compound of tannin; is taken orally to treat dyspepsia, enteritis,
enterocolitis; does not bind to enzymes in the gut and does not disturb digestion.

Bark of oak (Cortex Quercus) is used in the form of decoction; is
applied for gargling in stomatitis, gingivitis, paradontitis; may be also used to treat
burns, wounds.

Leaves of salvia (Folium Salviae), herb of sant-john’s-wort (Herba
Hyperici), flowers of chamomile (Flos Chamommillae) are used in the
form of infusions; they have astringent, anti-inflammatory, antimicrobial effects,
stimulate regeneration of tissues; indications are similar to indications for the use of the oak bark; are widely used in dentistry.

Bismuth subnitrate is non-organic astringent; is taken orally in ulcer of the
stomach and duodenum, enterocolitis; is applied topically to treat wounds, ulcers,
and burns of skin.