NS#7 | CD38 & NAD | FDA Approves Premature Aging Drug | 71 Year Old Powerlifter | Dr. de Grey Event

Описание: #NAD #CD38 #davidsinclair #aubreydegrey #valterlongo #newsletter #senescentcells

In this week's episode we will talk about a two studies looking at CD38, senescent cells and how between them they consume NAD. This came to us from a tweet by Dr. David Sinclair. A couple of news items, one about the FDA approving a drug for progeria, a genetic disease that causes premature aging and another at a 71 year old power lifterthat broke world records. And then we have two events, one with Dr. Aubery de Grey and the next installment of the NUS Healthy Lifespan webinar with Dr. Valter Longo.


Dr. Sinclair's tweet. -
  / 1328865337513795584  
Note his link to the article does not work
Main article
https://www.nature.com/articles/s4225...
Which has links to the two studies
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
https://www.nature.com/articles/s4225...
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels
https://www.nature.com/articles/s4225...
FDA Approves First Treatment for Hutchinson-Gilford Progeria Syndrome and Some Progeroid Laminopathies
https://www.fda.gov/news-events/press...
Association of Lonafarnib Treatment vs No Treatment With Mortality Rate in Patients With Hutchinson-Gilford Progeria Syndrome
https://pubmed.ncbi.nlm.nih.gov/29710...
Rudy Kadlub
https://www.cbssports.com/general/new...
  / rudykadlub  
Can rejuvenation technologies restore immune function and protect us from COVID-19? Including an intimate Q&A with Dr. Aubrey de Grey.
https://www.eventbrite.co.uk/e/rejuve...
https://nus-sg.zoom.us/webinar/regist...
Healthy Longevity - National University of Singapore