Chediak–Higashi Syndrome | Hematological Diseases | Giant Granules in Leukocytes | BMLS
Автор: Shrii!!!!BMLS Pathshala
Загружено: 2026-02-12
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Описание:
Chediak–Higashi Syndrome | Hematological Diseases | Giant Granules in Leukocytes | BMLS
Chediak–Higashi Syndrome (CHS) is a rare autosomal recessive hematological disorder characterized by giant cytoplasmic granules in leukocytes, recurrent infections, and partial albinism.
In this video, we explain definition, cause, pathogenesis, peripheral blood smear findings, clinical features, diagnosis, and exam-oriented points in simple language for BMLS students.
This topic is highly important for Hematological Diseases – BMLS, BMLT, DMLT & MLT exams.
🧬 Topics Covered
🔬 What is Chediak–Higashi Syndrome?
🧬 Genetic cause (LYST gene mutation)
🧫 Peripheral Blood Smear findings
🩸 Giant granules in neutrophils
🦠 Immunodeficiency & recurrent infections
🎨 Partial albinism
📚 Viva & University exam questions
🧪 Peripheral Blood Smear Feature
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🔎 Key Finding:
Presence of large, abnormal azurophilic granules in neutrophils and other leukocytes.
🔍 High-Ranking Keywords / Tags
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Autosomal recessive blood disorder
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Hematological diseases BMLS
Neutrophil granule abnormality
BMLS hematology notes
BMLT hematology
DMLT hematology
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