Lean Mass Hyper-Responders: An Exception to the Cholesterol Rule? - Revisited

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0:00 - Introduction
1:11 - Study Background
2:59 - Plaque in the Arteries
3:48 - Is ApoB linked to Plaque?
4:09 - Plaque begets Plaque
5:01 - Corrections and Critiques
5:53 - Pre-Registration Critique and Unreported Outcomes
7:51 - Absolute Plaque Growth Critique
17:38 - Lack of ApoB association Critique
21:43 - Take-Aways
23:18 - Quick Word of Thanks and Spiders

References
[Study 436] Soto-Mota A, Norwitz NG, Manubolu VS, et al. Plaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial. JACC Adv. Published online March 18, 2025. doi:10.1016/j.jacadv.2025.101686

Funding/Conflicts: Non-Profit Funding [Citizen Science Foundation] // Potential direct Conflicts of Interest [Dr. Nicholas Norwitz is a co-author of a Mediterranean low-carbohydrate diet cookbook. He donates all royalty payments from the book to nutrition research and education; David Feldman has received financial contributions through membership platforms (e.g., Patreon) to support ongoing research and is a partner in Own Your Labs LLC; All other authors reported no conflicts of interest relevant to the contents of the paper.]

Dr. Nicola Guess: https://drguess.substack.com/p/lean-m...
Dr. Stanfield:    • The Keto Cholesterol Study Has Gone HORRIB...  
Dr. Kevin Klatt: https://kcklatt.substack.com/p/keto-l...
Alex Leaf: https://alexleaf.com/lean-mass-hyper-...
Dr. Norwitz Rebuttal:    • A Lean Mass Hyper-Responder and Researcher...  
Dr. Budoff Rebuttal:    • Keto-CTA Study Confusion: Addressing the M...  

My Original Video:    • Lean Mass Hyper-Responders: An Exception t...  

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