Sleep & Epigenetics: Understanding the Genetic Links to Sleep Health

Описание: In this episode, we explore the fascinating role of epigenetics in sleep and sleep disorders. Our guest, Dr. Rene Cortese, a researcher in the Departments of Pediatrics and Obstetrics and Gynecology at the University of Missouri School of Medicine, brings his expertise in epigenetics and complex diseases to the discussion. Dr. Cortese’s research focuses on how complex diseases develop, progress, and are inherited, with a special emphasis on identifying potential treatments. His current work examines epigenetic mechanisms in genome regulation, especially those affecting children's and women's health.

Hope you find this episode insightful!

Reference: Cortese R. Epigenetics of Sleep Disorders: An Emerging Field in Diagnosis and Therapeutics. Diagnostics (Basel). 2021 May 10;11(5):851. doi: 10.3390/diagnostics11050851. PMID: 34068472; PMCID: PMC8150507.

Timelapse:
00:00 Introduction
02:09 What made you think of sleep in the context of epigenetics?
03:47 What is epigenomics?
06:52 Mechanisms of epigenetics
10:10 Epigenetic implications for sleep
12:05 What is the evidence of epigenetics in sleep disorders?
14:50 Clinical applications
16:10 Knowledge gaps
19:48 Clinical applications for sleep disorders
21:15 What about insurance companies?
22:22 What’s next in research?
23:53 Could sleep apnea during pregnancy affect offspring?
28:30 Final words

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Disclosure:
The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.