Infectious Disease & Parasite Pathology Cases/Board Review (for UPenn Pathology Residents 2024)

Описание: 👉 Playlist of all my infectious dermpath videos here:    • Infectious Dermpath & Pathology  

List of entities discussed (click timestamp to go to that part of video):
(note: not all of these entities are infectious - I added in some other things too)

Scurvy 0:04
RBCs in dermis - Real Hemorrhage vs Artifactual? 1:19
Rhinosporidiosis 9:06
Giardia 14:15
Entamoeba histolytica 19:27
Head lice/louse with nit (and body louse video) 25:02
Skeletal muscle atrophy & normal histology 28:36
Skeletal muscle looks like soap bubbles on PAS green counterstain 39:29
"Woo Cheal Cho lesion" (Verruca Plana/EDV with eosinophilic inclusions) 41:45
Classic EDV verruca plana with blue-grey cytoplasm 46:59
Classic verruca plana (flat wart) 47:54
Acne keloidalis nuchae (folliculitis nuchae) 50:33


Links & more info: 

Scurvy 
Scurvy digital slide: https://kikoxp.com/posts/2053

Clinical photos: https://www.nejm.org/doi/10.1056/NEJM...

Our scurvy paper: 
Kern M, Gardner JM. Mucocutaneous Manifestations of Scurvy. N Engl J Med. 2020 May 14;382(20):e56. doi: 10.1056/NEJMicm1911315. PMID: 32402165. https://pubmed.ncbi.nlm.nih.gov/32402...

Scurvy presenting as eosinophilic fasciitis clinically:

SCHULZ EJ, SWANEPOEL H. Scorbutic pseudoscleroderma: an aspect of Bantu siderosis. S Afr Med J. 1962 May 12;36:367-72. PMID: 13909538. https://pubmed.ncbi.nlm.nih.gov/13909...

Ahangari D, Gillard M, Certad G, Bataille M, Lasek A, Modiano P. Scurvy presenting as pseudo-scleroderma of the leg. JAAD Case Rep. 2019 Sep 3;5(9):831-833. doi: 10.1016/j.jdcr.2019.07.019. PMID: 31517009; PMCID: PMC6731345. https://pubmed.ncbi.nlm.nih.gov/31517...

Appiah MM, Bohrer N, Galati A, Vuong C, Tucker SM, Hightower G. Vitamin C deficiency presenting as pseudoscleroderma in a pediatric patient with food aversion. JAAD Case Rep. 2023 Dec 29;44:82-84. doi: 10.1016/j.jdcr.2023.12.008. PMID: 38304101; PMCID: PMC10831238. https://pmc.ncbi.nlm.nih.gov/articles...


Rhinosporidiosis

Pics: https://kikoxp.com/posts/5703

Giardia: 

Pics: https://kikoxp.com/posts/10000 
Blog post: https://parasitewonders.blogspot.com/...


Entamoeba: 

Pics: https://kikoxp.com/posts/50070

Examples of Entamoeba coli cysts from Bobbi Pritt aka ParasiteGal:
https://parasitewonders.blogspot.com/...
https://parasitewonders.blogspot.com/...

Tip from Dr. Bobbi Pritt (@ParasiteGal) for telling amoeba trophozoites apart from histiocytes:
"PAS can help sometimes as it stains the trophozoites deep magenta. Check out the trophs in this case of amebic liver 'abscess': https://s3.us-east-2.amazonaws.com/ma... "

Info about amebiasis from the CDC: https://www.cdc.gov/dpdx/amebiasis/in...


"Woo Cheal Cho" EDV lesion: 

Pics of my case: https://kikoxp.com/posts/50074

Publication by Dr. Cho's group: 
Bartley BR, Huen A, Rady PL, Tyring SK, Nagarajan P, Aung PP, Curry JL, Ivan D, Torres-Cabala CA, Prieto VG, Cho WC. Eosinophilic homogeneous intracytoplasmic inclusion bodies: Unique viral cytopathic changes associated with epidermodysplasia verruciformis and human papillomavirus type 49. J Cutan Pathol. 2022 Jul;49(7):658-662. doi: 10.1111/cup.14221. Epub 2022 Mar 21. PMID: 35262953. https://pubmed.ncbi.nlm.nih.gov/35262...

Epidermodysplasia verruciformis (EDV)
Video (101):     • Epidermodysplasia verruciformis (EDV) 101  
Images: https://kikoxp.com/posts/8614
WSI digital slide (best case ever): https://kikoxp.com/posts/19127
WSI digital slide (SCC in situ plus EDV): https://kikoxp.com/posts/24374

Verruca plana (flat wart)
Video:    • Verruca Plana (Flat Wart under the microsc...  Pics: https://kikoxp.com/posts/50072

Verruca vulgaris (common wart)
Video 101:    • Wart under microscope.Verruca 101: More th...  
Short video:    • Wart Under the Microscope (Verruca Vulgari...  

Acne keloidalis: 
clinical pics: https://www.wikidoc.org/index.php/Acn...

Alopecia dermpath guru, Dr. Len Sperling, has suggested that acne keloidalis is closely related to scarring/cicatricial alopecias (like CCCA) - here's a paper he wrote about this: https://jamanetwork.com/journals/jama...


A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

You might like my Twitter/social media 101 guide: https://kikoxp.com/posts/15217

Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks. A look inside & info about where to buy them here: https://kikoxp.com/posts/17787

This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.