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Can Cannabis Reverse Brain Aging? Insights into Your 2025 Study

Автор: Dr. Misha Kogan

Загружено: 2025-08-25

Просмотров: 231

Описание: Could cannabis actually help reverse age-related brain changes? In today’s 12min video, we dive into a groundbreaking preprint study suggesting that cannabis use may align brain connectivity patterns with those seen in younger adults—alongside boosting cognitive performance.

Data Source & Scale: Utilized the UK Biobank’s neuroimaging and behavioral data from over 25,000 participants .

Objective: To examine how cannabis use interacts with brain aging, particularly through patterns of functional network connectivity (FNC)—a measure of how different brain regions communicate.

Key Finding: Cannabis users showed brain network configurations similar to younger individuals, especially in connectivity between subcortical and sensorimotor regions, and between subcortical and cerebellar regions.

Cognitive Advantage: These users also performed better across several cognitive domains—suggesting a potential protective or rejuvenating role of cannabis on brain function

This preprint suggests cannabis may influence brain architecture in a way that mirrors youthful connectivity—a finding that resonates with other research on cannabinoids’ neuroprotective effects:

They may reduce neuroinflammation, excitotoxicity, and oxidative stress, all key drivers of dementia and cognitive decline.

Clinical studies have hinted that THC/CBD formulations can alleviate behavioral and psychological symptoms in advanced dementia—with good safety profiles and possible medication deprescribing benefits
Wall Street Journal

In more broader terms exogenous cannabinoids offer multilayered neuroprotection, targeting core mechanisms of neurodegeneration—like inflammation and oxidative damage. They show real-world promise in improving symptoms and reducing polypharmacy in patients with advanced dementia.

This new study suggests cannabis may even enhance or preserve cognitive function long before dementia takes hold, shifting the paradigm from symptomatic care to proactive brain health.

It's important to remember:
The study is observational and explores correlations—not causation.

Cannabis’s complex pharmacology, individual differences in dosage and formulation, and long-term safety—especially in older or demented populations—remain open questions

But in short: cannabis may help preserve youthful brain networks and bolster cognitive function—and with further validation, it could revolutionize dementia care. If you're fascinated and want to hear more about clinical trials, your questions, or deeper mechanisms, leave a comment below—and don’t forget to hit Subscribe for more cutting-edge insights.

Here is the link for preprint: https://www.researchsquare.com/articl...

And also here is the link to last year's article in Wall Street Journal discussing how cannabis is currently used for patients with various demential related symptoms:

https://www.wsj.com/health/wellness/d...

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Can Cannabis Reverse Brain Aging? Insights into Your 2025 Study

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