When Your Brain Turns Against You: What PMDD Depression feels like

Описание: They call it “depression.”
But in PMDD, it feels like your mind has been hijacked…like an evil twin takes over and sees the world through a dark filter you can’t escape.

Here’s the science of why that happens:

🧠 During the luteal phase, progesterone rises and turns into a neurosteroid called allopregnanolone (ALLO).
In most brains, ALLO calms anxiety through GABA receptors.
But in PMDD brains, it disrupts them — so the emotional centre (the amygdala) goes into chaos, and the prefrontal cortex, the part that controls rational thought, disconnects.
At the same time, serotonin transporters become overactive, pulling serotonin out of your brain’s circuits, leaving you in despair, unable to think your way out.

You’re not broken.
It’s not weakness.
It’s neuroscience, and you can learn to work with your brain again.

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