Advancing ADC Development: End-to-End Solutions from Design to Characterisation
Автор: Eurofins Discovery
Загружено: 2025-06-16
Просмотров: 376
Описание:
ADC (Antibody-Drug Conjugate) drug discovery is a specialised approach in pharmaceutical research and development that focuses on creating targeted therapies. ADCs combine the targeting ability of monoclonal antibodies with the cell-killing power of cytotoxic drugs. The goal is to deliver a potent drug directly to the target cells while minimising damage to healthy surrounding tissue.
Developing an Antibody-Drug Conjugate (ADC) is a complex process that requires careful consideration of several key factors to ensure efficacy, safety, and manufacturability. Here are the main factors that need to be considered, including:
• Antibody selection
• Cytotoxic drug selection
• Linker chemistry
• Conjugation chemistry
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