13: Dr. Su Golder on Reporting Adverse Events in Clinical Research

Описание: Dr. Su Golder, associate professor and senior research fellow in the Department of Health Sciences at the University of York, has dedicated a significant portion of her career to improving the reporting of adverse events in clinical research. In this episode, she speaks with host Deborah Borfitz about why adverse events are vital to address but often difficult to ascertain for any given therapeutic intervention.  

Golder talks about the strategic ways data can be manipulated—often leading to underreporting or misleading reporting—and the preferred guidelines that help researchers relay accurate information to clinicians and patients. She also discusses why data from randomized controlled trials are not always the best indicator of adverse advents in the real world and why social media provides valuable insights into why patients discontinue drug usage even when symptoms are considered minor. She says, “If something stops a patient from taking [a drug], then it doesn’t matter how effective [that drug] is. So [patient experience] is the most important thing.”  

For all articles and sources mentioned in this episode, visit http://bit.ly/4lJRRx6

Subscribe to the podcast on Apple Podcasts and leave a review to support the show. Join us at Scope Europe on October 14-15 in Barcelona - use code SOT10 for an additional 10% discount.

_______________________________________________

ABOUT SU GOLDER, PhD, MSc, UNIVERSITY OF YORK:

Dr. Su Golder is an associate professor within the Health Services and Policy Research group at the University of York. She has a background as an information specialist with over 25 years of experience in literature searching. Golder has specialist expertise and teaching experience in systematic review methodology, systematic reviews of adverse effects, and using social media as a data source.

Her Ph.D. was funded by the Medical Research Council and has made an important contribution to retrieving information on adverse effects nationally and internationally. During her post-doctoral National Institute for Health Research fellowship, she expanded her work by investigating the use of unpublished data, text mining, and social media in the retrieval of adverse effects data. In her current research, she undertakes systematic reviews, develops systematic review methodology, conducts network analyses, and uses social media to gain wider information and healthcare user and provider perspectives. She is currently an elective member of the Cochrane Methods Executive and one of the founders and co-convenors of the Cochrane Adverse Effects Methods Group.

____________________________________________

The Scope of Things podcast explores clinical research and its possibilities, promise, and pitfalls. Clinical Research News senior writer, Deborah Borfitz, welcomes guests who are visionaries closest to the topics, but who can still see past their piece of the puzzle. Focusing on game-changing trends and out-of-the-box operational approaches in the clinical research field, the Scope of Things podcast is your no-nonsense, insider’s look at clinical research today.

Links from this episode:
Clinical Research News (https://www.clinicalresearchnewsonlin...)
University of York (https://www.york.ac.uk/)
Adverse Event Reporting May Need A Total Redo (http://bit.ly/3nn1okO)
Medicines & Healthcare products Regulatory Agency Yellow Card reporting (https://yellowcard.mhra.gov.uk/)
Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) (http://www.prisma-statement.org/)
PRISMA harms checklist: improving harms reporting in systematic reviews (https://www.bmj.com/content/352/bmj.i157)
Consolidated Standards of Reporting Trials (CONSORT) (https://www.goodreports.org/reporting...)
OpenTrials: towards a collaborative open database of all available information on all clinical trials (https://trialsjournal.biomedcentral.c...)
Cochrane Adverse Effects Methods Group (https://methods.cochrane.org/adversee...)