Chelation in relation to Biological Activity of drug 🔥 | Medicinal Chemistry-I | B.Pharm Semester IV

Описание: Welcome to *Professor Akansha’s Classroom* 👩‍🏫

In this lecture, we explore an important physicochemical property that affects biological activity:

Video Notes : https://shorturl.at/A7EfS

🔬 *Chelation*

Chelation refers to the formation of a *stable ring complex between a metal ion and a drug molecule* containing donor atoms like oxygen, nitrogen, or sulfur.

In this lecture, you will understand:

✔ What is chelation?
✔ Difference between chelation and coordination
✔ Bidentate & polydentate ligands
✔ Stability of chelate rings
✔ Role of electronegativity & lone pairs
✔ Chelation in biological systems
✔ Effect on drug absorption
✔ Chelation & reduced bioavailability
✔ Chelation in drug mechanism
✔ Therapeutic chelating agents
✔ Examples: EDTA, Dimercaprol, Tetracycline, Penicillamine

---

🧪 Why Chelation is Important in Medicinal Chemistry?

Chelation can:

✔ Reduce drug absorption (e.g., tetracycline with milk)
✔ Increase drug stability
✔ Alter biological activity
✔ Detoxify heavy metals
✔ Affect distribution & elimination

This topic is very important for:

• B.Pharm Semester IV Exams
• GPAT
• NIPER
• Pharmacist exams
• Viva & MCQs

---

🔔 Stay Connected

📺 Subscribe to YouTube:
[   / @professorakansha  ](   / @professorakansha  )

📸 Follow on Instagram:
[  / professorakansha  ](  / professorakansha  )

Like 👍 Comment 💬 Share 🔁 Subscribe 🔔

Let’s make Medicinal Chemistry simple together ❤️

---


chelation medicinal chemistry, chelating agents pharmacy, metal drug interaction, EDTA medicinal chemistry, tetracycline chelation, dimercaprol chelation, penicillamine drug action, medicinal chemistry bpharm semester 4, chelation biological action, drug metal complex formation, physicochemical properties drugs, chelation exam questions pharmacy, pharmacy semester IV topic, GPAT medicinal chemistry chelation, NIPER preparation topic, chelation and bioavailability, chelation drug absorption, medicinal chemistry lecture, professor akansha pharmacy, chelation examples drugs, pharmaceutical chemistry lecture, drug stability chelation, chelation and toxicity, heavy metal poisoning treatment, medicinal chemistry important topic, pharmacy mcqs chelation, chelation simplified, pharmacy theory class, drug interaction chelation, chelation mechanism explanation

---


#Chelation #MedicinalChemistry #BPharm #PharmacyStudents #ChelatingAgents #DrugAction #EDTA #Tetracycline #ProfessorAkansha #GPATPrep #NIPERPrep #PharmaLife #SemesterIV #PharmacyEducation #DrugMechanism#Physicochemical Properties in relation to biological action

---


chelation medicinal chemistry, chelating agents pharmacy, metal drug complex formation, EDTA tetracycline chelation, chelation biological action, medicinal chemistry BPharm semester IV, chelation and bioavailability, drug metal interaction pharmacy, heavy metal poisoning treatment EDTA, GPAT medicinal chemistry chelation topic, pharmacy exam chelation questions

---