TORSEMIDE API MANUFACTURER & EXPORTER NIKSAN PHARMACEUTICAL

Описание: Torsemide is one type of diuretic medication which is used to treatment of heart failure, liver disease, kidney disease and high blood pressure.

SYNONYMS: Torasemida, Torasemide, Torasémide, Torasemidum, Torsemide

IUPAC NAME:1-({4-[(3-methylphenyl) amino] pyridin-3-yl} sulfonyl)-3-(propan-2-yl) urea

CAS NO: 56211-40-6

FORMULA: C16H20N4O3S

MOLECULAR MASS: 348.42 g/mol

STORAGE OF TORSEMIDE: Store it in cool and dry place. Torsemide is light sensitive drug so keep away from light and also put it in the light resistance container. Properly discard this product when it is expired or no longer needed. Keep away from reach of children and pets.

APPLICATIONS OF TORSEMIDE: Torsemide is used in treatment of high blood pressure, heart failure, liver disease and kidney disease.This drug also can reduce many symptoms like shortness of breath and swelling in your arms, legs, and abdomen.

HOW TO USE: Simply take the medicine as per your doctor says. Torsemide is taken by mouth or by I.V. injection. Take this drug on a regular basis to get the most benefit from it.
Dosage is based on your medical condition and response to treatment. Continue to take Torsemide even if you feel well. Do not stop taking Torsemide without talking to your doctor. It is best to avoid taking this medicine within 4 hours of your sleeping time it will effect on your urine.

HOW TORSEMIDE WORKS: Torsemide works by eliminating the unneeded water of body by urination.

CONTRAINDICATIONS OF TORSEMIDE: If you have high amount of triglyceride in the blood kindly avoid taking Torsemide. Do not take Torsemide if you have an acid-base imbalance of the blood or decreased blood volume. Kindly avoid Torsemide if you have hardening of the liver, hearing loss and high amount of uric acid in the blood.

PHARMACOKINETICS OF TORSEMIDE: Torsemide is rapidly and fairly absorbed independent of the heart failure state. Half-life of Torsemide in normal patient is 3.5 hours. Both hepatic metabolism circulations are cleared by Torsemide. Peak plasma concentration of Torsemide was 10.1µg/ml. In a normal patient, about 20% is excreted through urine and 80% is excreted by both hepatic metabolic systems.

SIDE EFFECTS OF TORSEMIDE: Many people using this medication do not have serious side effects. Other common side effect of Torsemide is Dizziness or headache. In rare cases there is a signs of kidney problem like change in the amount of urine. In the very rare case signs of allergic reaction like rash andswelling are seen in patient.

PRECAUTIONS: If you are allergic to Torsemide, tell your doctor or pharmacist before taking Torsemide. If you have kidney problems, liver problems, inability to make urine kindly tell your doctor about it. This drug makes you dizzy so kindly avoid driving, handling machinery. Don’t take alcohol and cannabis after consuming this medicine. Tell your doctor for advice if you see any side effects.

CDSCO APPROVAL:
Torsemide 10mg + Amiloride 5mg tablets are approved by CDSCO in India in 17.01.2007

FORMULATION AVAILABLE IN MARKET:
Torsemide 5 MG Tablets
Torsemide 10 MG Tablets
Torsemide 20 MG Tablets
Torsemide 40 MG Tablets
Torsemide 100 MG Tablets
Amiloride 5 MG+Torsemide 10 MG Tablets
Torsemide 10 MG+Spironolactone 50 MG Tablets
Torsemide 20 MG+Spironolactone 25 MG Tablets
Torsemide 5 MG+Spironolactone 50 MG Tablets
Torsemide 20 MG+Spironolactone 50 MG Tablets
Eplerenone 25 MG+Torsemide 10 MG Tablets
Spironolactone 100 MG+Torsemide 10 MG Tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult