When, why and how tumour clonal diversity predicts survival

Описание: The utility of intratumour heterogeneity as a prognostic biomarker is the subject of ongoing clinical investigation. We use a spatial computational model of tumour evolution to assess forecasting of tumour growth and survival. Our work offers explanations for empirical findings and contributes to the development of predictive oncology. Publication: https://doi.org/10.1111/eva.13057