All you need to know about Microscreen Sickle Cell Test. Part 1: Kit contents
Автор: Tackle Sickle Cell Africa (TSCA)
Загружено: 2025-12-23
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The MicroScreen Sickle Cell HbA/HbS/HbC RDT Kit is a rapid, qualitative immunochromatographic assay designed for the simultaneous detection of hemoglobin A (HbA), hemoglobin S (HbS), and hemoglobin C (HbC) in human whole blood samples, aiding in the diagnosis of sickle cell disorders.
Developed by Microhaem Scientifics (MHS), a Uganda-based company focused on diagnostic solutions, this point-of-care test kit operates on the principle of antibody-antigen agglutination using nano gold particles for visible results, making it suitable for venous or capillary blood without requiring lab equipment or electricity.
The procedure is straightforward: add a blood sample to the test cassette along with buffer, and interpret the lines (control, HbA, HbS, HbC) at exactly 10 minutes for validity—results are not reliable beyond that timeframe.
With 100% sensitivity and specificity for whole blood detection, a shelf life of 24 months at 2–30°C, and no need for refrigeration, it's particularly advantageous for community screenings in high-burden, resource-limited areas like rural Africa, where organizations such as Tackle Sickle Cell Africa have deployed it for early identification of sickle cell trait (e.g., HbAS) and disease.
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