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Pfizer-BioNTech vaccine is effective against strains in U.K., South Africa: BioNTech CEO

Автор: CNBC Television

Загружено: 2021-01-11

Просмотров: 16069

Описание: BioNTech CEO Ugur Sahin joined "Squawk Box" on Monday to discuss how effective the Pfizer-BioNTech's coronavirus vaccine is at protecting against the variants of the virus researchers have documented in South Africa and the United Kingdom. For access to live and exclusive video from CNBC subscribe to CNBC PRO: https://cnb.cx/2NGeIvi

A coronavirus vaccine developed by Pfizer and BioNTech appears to be effective against a key mutation in the more infectious variants of the virus discovered in the U.K. and South Africa, according to a study conducted by the U.S. pharmaceutical giant.

It comes as countries scramble to contain the variants that are significantly more transmissible, with public health experts anxious about the potential impact on inoculation efforts.

The research, published Thursday on preprint server bioRxiv and not yet peer-reviewed, suggested the Pfizer-BioNTech vaccine worked to neutralize the so-called N501Y mutation.

The N501Y mutation has been reported in the more infectious variants. It is altering an amino acid within six key residues in the receptor-binding domain — a key part of the spike protein that the virus uses to gain entry into cells within the body.

“These findings are good news for the likely effectiveness of the Pfizer/BioNTech vaccine against these new variants of SARS-CoV-2,” said Dr. Michael Baker, an epidemiologist at the University of Otago in Wellington, New Zealand.

“In other words, the Pfizer vaccine is likely to induce immunity that covers the two new more infectious variants originating in England and South Africa,” he added.

Pfizer and researchers at the University of Texas Medical Branch conducted the study on blood taken from people who had been given the Covid-19 vaccine.

The findings are limited, however, because the study does not look at the full set of mutations found in either of the new rapidly spreading variants.

“Pfizer and BioNTech have tested sera from people immunized with the BNT162b2 vaccine for its ability to neutralize multiple mutant strains,” a Pfizer spokesperson told CNBC via email on Friday, referring to the official name of the Covid vaccine.

“To date, we have found consistent coverage of all the strains tested. The two companies are now generating data on how well sera from people immunized with BNT162b2, may be able to neutralize new strains.”

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Pfizer-BioNTech vaccine is effective against strains in U.K., South Africa: BioNTech CEO

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