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ADVANCES IN MASS SPECTROMETRY FOR THE ANALYSIS AND BIOANALYSIS OF ANTIBODY DRUG CONJUGATES
Автор: Biopharma Webinar Series
Загружено: 2021-08-09
Просмотров: 669
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Presented by Arnaud Delobel, PhD, R&D Director at Quality Assistance sa
ADCs are complex compounds resulting from the coupling of cytotoxic small molecules to a monoclonal antibody. Their characterization as well as their bioanalysis (quantification in biological fluids) remains challenging. Mass spectrometry at different levels (intact, middle, peptide) can be a valuable tool, and can now be used in a regulated environment.
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