Chimpanzees have the capacity to create meaningful communication through vocalizations

Описание: Description: After more than 20 years of using the flawed human reference genome as a standard for genetic research, the Human Pangenome Reference Consortium (HPRC) has made groundbreaking progress in characterizing the fraction of human DNA that varies between individuals. Using advanced sequencing and computational methods, the HPRC assembled genomic sequences of 47 people from around the world into a pangenome in which more than 99 percent of each sequence is rendered with high accuracy. The pangenome, which is public and can be used by scientists around the world, represents significantly more accurate human genetic diversity than has ever been captured before. With a greater breadth and depth of genetic data, researchers can refine their understanding of the link between genes and disease traits, and accelerate clinical research. The HPRC's effort is a critical step towards reducing the inherent bias in biomedical data and addressing health disparities affecting patients today.
image credit-The Human Pangenome Reference Consortium has made significant progress in creating a more inclusive human reference genome by assembling genomic sequences of 47 individuals from around the world. The original human reference genome was based on data from a single individual of African-European background, limiting its representation of genetic diversity. This new pangenome, which renders over 99% of each sequence with high accuracy, reveals almost 120 million DNA base pairs previously unseen. By providing a more accurate representation of human genetic diversity, researchers can refine their understanding of the link between genes and diseases, accelerate clinical research, and ultimately help address health disparities.
2nd-The new draft pangenome reference contains 47 genomes instead of just one, and will provide a much better point of comparison than the traditional reference to find and understand the differences in our DNA. Credit: National Human Genome Research Institute
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