Microbiology 71= Sterilization (Part- 10)= Chemical Method of Sterilization | Chemical Sterilization

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Sterilization refers to any process that removes, kills, or deactivates all forms of life (in particular referring to microorganisms such as fungi, bacteria, spores, unicellular eukaryotic organisms such as Plasmodium, etc.) and other biological agents like prions present in a specific surface, object or fluid, for example, food or biological culture media.

Chemical sterilization is typically used for devices that would be sensitive to the high heat used in steam sterilization, and for devices that may be damaged by irradiation (rubbers and plastics can become more brittle after irradiation.) Often chemical sterilizers function by using low temperature, highly reactive gases that come into direct contact with the test article. For reusable devices (such as those used in hospitals) chemicals are often used for repeated disinfection after each use (disinfection is a different process from sterilization). The chemical(s) and procedure used must be validated. In this case it is important to perform a reusable device cleaning and disinfection validation.

Chemicals Used for Sterilization or Disinfection
Ethylene Oxide
Ozone
Bleach
Glutaraldehyde and Formaldehyde
Phthalaldehyde
Hydrogen Peroxide
Peracetic Acid
Silver

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