Tablets। Introduction। Classifiction । Advantages । Disadvantages । Pharmaceutics ।U-1।L-4।Pharmacy

Описание: Tablets। Introduction। Classifiction । Advantages । Disadvantages । Pharmaceutics ।U-1।L-4।Pharmacy



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#advantagesoftablets


Introduction-
• According to USP, Tablet is defined as a compressed solid dosage form containing
medicaments with or without Excipients.
• According to the Indian Pharmacopoeia, Pharmaceutical tablets are solid, flat or
biconvex dishes, unit dosage form, prepared by compressing a drug or a mixture of
drugs, with or without diluents
Advantages of tablet dosage form over other oral drug delivery systems
From patients stand point:
• They are easy to carry, easy to swallow and they are attractive in appearance.
• Unpleasant taste can be masked by sugar coating and they do not require any
measurement of dose.
• Some of the tablets are divided into halves and quarters by drawing lines during
manufacturing to facilitate breakage whenever a fractional dose is required.
From the standpoint of manufacturer:
• An accurate amount of medicament, even if very small, can be incorporated.
• Tablets provide best combined properties of chemical, mechanical and microbiological
stability of all the oral dosage forms.
• Since they are generally produced on a large scale, therefore, their cost of production
is relatively low, hence economical.
• They are in general the easiest and cheapest to package and ship among all oral dosage
forms.
• Some specialized tablets may be prepared for modified release profile of the drug.
• Product identification is potentially the simplest and cheapest requiring no additional
processing steps when employing an embossed or monogrammed punch face.
Disadvantages of tablet dosage form
 Difficult to swallow in case of children and unconscious patients.
 Drugs with poor wetting, slow dissolution properties, optimum absorption high in GIT
may be difficult to formulate or manufacture as a tablet that will still provide adequate
or full drug bioavailability.
 Bitter testing drugs, drugs with an objectionable odor or drugs that are sensitive to
oxygen may require encapsulation or coating. In such cases, capsule may offer the best
and lowest cost.
 Some drugs resist compression into dense compacts, owing to amorphous nature, low
density character.
Types of tablets-
(a) Tablets ingested orally:
• Compressed tablets
• Multiple compressed tablets


notes pdf link _https://drive.google.com/file/d/1ziGY...