What is Triplet Therapy, Benefits & Side Effects for Advanced Prostate Cancer I Dr. Rana McKay – 145

Описание: #ProstateCancer #MensHealth #AdvancedProstateCancer #ADT

In this powerful episode of the Dr. Geo Prostate Podcast, Dr. Geo welcomes back Dr. Rana McKay, a top oncologist from UC San Diego, to dive deep into triplet therapy for advanced prostate cancer. Learn what triplet therapy is, who it's for, how it compares to doublet therapy, and why it might be changing the game in prostate cancer treatment.

Whether you're a patient, caregiver, or practitioner, this episode helps clarify complex terms like ADT, ARPI, Docetaxel, and castration-resistant prostate cancer (CRPC)—and it’s all delivered with compassion and real-world clinical insight.

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🎧 Listen now to understand your options and make more informed decisions in your prostate cancer journey.

📚 Chapters
00:00 – Introduction: What is triplet therapy?
02:00 – Defining doublet vs. triplet therapy
03:00 – The backbone of prostate cancer treatment
04:30 – FDA approval and off-label use of triplet therapy
05:30 – Role of ADT agents like Relugolix
06:30 – Personalizing therapy: Doublet vs. triplet candidates
08:00 – Landmark trials: CHAARTED, TITAN, LATITUDE, PEACE-1, ARASENS
10:00 – Who benefits most from triplet therapy?
12:00 – Low volume vs. high volume metastatic disease
14:00 – Delaying castration-resistant prostate cancer (CRPC)
16:30 – Why early treatment intensification matters
18:00 – Survival outcomes: Overall survival vs. prostate cancer-specific survival
21:00 – Understanding patient values and treatment fears
23:00 – Discussing chemo side effects: What patients actually experience
26:00 – The role of Decadron and cryotherapy in managing side effects
28:00 – Duration of triplet therapy and possibility of stopping ADT
30:00 – Intermittent vs. continuous hormone therapy
33:00 – ARPI and ADT options: Enzalutamide, Abiraterone, Darolutamide, Relugolix
36:00 – Cost, quality of life, and access: Choosing the best combination
38:00 – Why integrative oncology matters
41:00 – Cold cap therapy and exercise during treatment
43:00 – Summary: Demystifying chemotherapy and fostering patient-centered care
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#ProstateHealth #AndrogenDeprivationTherapy #HormoneTherapy
#ProstateCancerTreatment #TripletTherapy #DoubletTherapy
#Docetaxel #ARPI
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DISCLAIMER: This audio is educational and not medical advice. The views expressed are my own and not those of my employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for any direct or indirect consequences, including economic loss, injury, illness, or death.