Big Pharmaceutical great treat isn't whatever u think;it's what you're doing with the information

Описание: Role of mulberry in ayurvedic system of medicine

Plants are the natural sources of biologically active compounds (Ji et al., 2009), which have received increased attention of medicinal practitioners and pharmaceutical industries across the globe over the years. Plant derived natural products were being used in preventing and curing the common diseases of human beings (Cao et al., 2018). Among the different plants, mulberry has been known worldwide for their biologically active biomolecules like phenols, alkaloids, terpenoids, amino sugars, stilbenoids etc. (Iqbal et al., 2012; Kiran et al., 2019). In India, mulberry is known as ‘Kalpa Vruksha’ as all the parts of it used in traditional system of ayurvedic medicine (Datta, 2000). It is highly recognized as a source of important phytopharmaceuticals, mineral ions (Zhang et al., 2017) and other nutritive compounds (Fig. 4). Hence extracts of this plant parts were being used traditionally in Indian ayurvedic system of medicine in curing several health ailments and for improving the human health (Ghosh et al., 2017).


Download : Download full-size image

Fig. 4. Role of mulberry in promotion of human health.

Morus nigra, a wild species of mulberry is being used traditionally by ayurvedic practitioners to cure rheumatis and arthritis (Perez et al., 2011). In Japan and Korea, mulberry leaves were consumed as an anti-diabetic medicine by diabetic patients as the leaves possess anti-diabetic molecules like 1-deoxynojirmycin, isobavachalcone, morachalcon, fagomine, quercetin etc. (Wang et al., 2013; Kiran et al., 2019). In China, mulberry leaves have been in use since hundreds of years ago to treat various diseases like hypertension, hyperglycemia, inflammation, fever, cough and cancer (Bown, 1995). Similarly, in China the young shoot tips and young leaf tips were boiled along with tea to control the blood pressure (Datta, 2000; Qin et al., 2012).
High anthocyanin content and antioxidant activities associated with phytochemicals present in the berries (mulberry fruits) have made them very popular and hence included in the human diet (Eyduran et al., 2015). Berries provide potential health benefits to human beings such as delay in aging process, protection from cardiovascular diseases, antidiabetic activity and reduced risk of cancer (Mnaa et al., 2015). Mulberry fruits were reported to possess high antioxidising nature (Guo et al., 2003), can prevent liver and kidney damage (Chen et al., 2016), improve eyesight (Yang et al., 2010a), strengthening the joints (Shizhen, 2008), treatment of sore throat, reduce blood pressure (Zhou et al., 2017), treatment of anemia, hypertension (Ma, 2002; Gong and Zhu, 2008), anti-helminthic (Gungor and Sengul 2008), anti-thrombotic (Yamamoto et al., 2006); anti-inflammatory (Kim and Park, 2006); can prevent formation of premature white hair formation (Liu et al., 2008) in human beings.
Dietary fiber of mulberry fruits was reported to decrease lipids in liver and increases the activity of low density lipoprotein (LDL) receptor (Venkatesan et al., 2003), hence consumption of mulberry fruits can be prescribed for lipid lowering action of hypercholesterolemia patients (Sirikanchanarod et al., 2016) and for reducing the risk of atherosclerosis (Chen et al., 2005). In addition consumption of mulberry fruits is proved beneficial in curing the brain damages like Alzheimer (Shih et al., 2010; Choi et al., 2012), Parkinson (Kim et al., 2010; Strathearn et al., 2014) and cerebral ischemia (Kang et al., 2006) and this fruit is also consumed for anti-aging effects (Shizhen, 2008; Zheng et al., 2014), anti-epileptic and anti-stress activities on human beings (Nade et al., 2010).
Mulberry fruit is rich in polyphenols like flavones, flavonols, isoflavanols, stilbenes, lignans, tannins, anthocyanins, catechins (Liu, 2004). Intake of berry fruits rich in polyphenols is associated with the reduced risk of cardiovascular diseases, cancers and neurodegeneration (Han et al., 2007; Del et al., 2013). Mulberry fruit extracts was also reported to prevent gastric cancer (Huang et al., 2011). Combination of leaf and fruit extracts of mulberry was reported for anti-diabetic and anti-obesity activity (Lim et al., 2013). Mulberry fruit extracts prevent the olfactory dysfunction and degeneration of dopaminergic neurons (Gu et al., 2017). Polysaccharide components of mulberry fruit were reported to possess the better preventive effects of inflammation and apoptosis than the polysaccharides of straw berry (Liu and Lin, 2014).
The mulberry fruit and syrup are also used to treat urine inconsistency, constipation, dizziness, throat infection, tinnitus, dyspepsia, melancholia, fever, depression and endemic malaria (Jain and De Filipps, 1991; Shivakumar et al., 1995). used for balancing internal secretions of humans and for enhancing immunity against infections (Venkatesh and Chauhan, 2008). Fruit syrups and recipes were used against insomnia, constipation,