Benefits of Anti-D in Rh Negative Pregnancy-Dr.Aruna Kumari of Cloudnine Hospitals | Doctors' Circle

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Anti- D is the immunoglobulin which is given to prevent the Rh Iso immunization means the antibodies and the antigens in the blood the blood group antigen. For example if the mother is negative blood group and the husband of her is positive blood group, the mixing of the
blood antigen and antibody this will lead to the formation of antibodies which will be destructing the fetal RBCS in the next pregnancy. If by chance that baby is positive in such scenario what we do is we do the blood group of for all pregnant women if the woman is Rh negative in her husband is positive. For blood group then ICT test indirect combs test we do at the first visit of pregnancy and at 28 weeks we do give NTD injection to prevent Rh Iso immunization for the next pregnancy. But the current guidelines tell that sometimes 40 % of the babies can be Rh negative. So there may be no need of giving Anti D at 28 weeks of gestation. But it is always better after delivery also to check the baby's blood group and then give the anti-day injection and definitely after a miscarriage Anti-D injection has to be taken. Because the blood group of that about us what it is we don't know in such scenario. Anti- D injection to the mother to be given like 150 micrograms in the miscarriage scenarios and 300 micrograms after the delivery based on the blood group is an ideal setting to prevent Rh related complications like fetal hydrops and need for repeated blood transfusion to the baby and risk of jaundice and neonatal morbidity can be prevented by this vaccination.
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