How does colon cancer metastasize?
Автор: IRB Barcelona
Загружено: 2012-11-13
Просмотров: 46392
Описание:
Scientists at IRB Barcelona discover a key process that allows colon cancer to metastasize
The study, published in the prestigious journal Cancer Cell, reveals that tumour cells of the colon must form alliances with healthy cells in order to colonize other organs during metastasis.
The presence of TGF-beta in the tumour's microenvironment forces healthy cells to produce interleukin-11 (IL-11), a protein that alters the genetic programme of the tumour cells and helps them to survive during metastasis.
This discovery opens the doors to substantial improvements in the diagnosis and treatment of patients with colon cancer.
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