Inside Patient #1’s Islet Transplant Without Immunosuppression
Автор: Diabetech
Загружено: 2026-02-23
Просмотров: 10819
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I spoke with the first patient in a groundbreaking type 1 diabetes cure research trial using encapsulated neonatal pig islet cells—without immunosuppression. Six months after his transplant through the OPF-310 study led by Otsuka Pharmaceutical and University of Illinois Chicago, Michael Revland's insulin needs have been cut in half as the cells have begun maturing and producing insulin. We dive into how this porcine islet cell transplant works, why it differs from stem cell and donor islet trials, and the risks and rewards of pursuing insulin independence. He also shares why he declined an immunosuppression-based transplant study and the emotional highs and lows of being patient number one.
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Chapters:
02:35 Islet Cell Therapy
07:49 Military Diagnosis
22:09 The Search For Trials
32:47 Eledon Trial
41:15 OPF-310 Study
58:05 Post Implant Results
01:07:29 The Dark Period
01:10:11 It’s Working
01:23:09 What’s Next
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