Antidepressant (Part 02) = Classification & Mechanism of Action of Antidepressant Drugs

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Depression is a mood disorder characterized by persistently low mood and a feeling of sadness and loss of interest. It is a persistent problem, not a passing one, lasting on average 6 to 8 months. Depression (major depressive disorder or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or working.

Bipolar disorder is different from depression, but it is included in this list is because of someone with bipolar disorder experiences episodes of extremely low moods that meet the criteria for major depression (called “bipolar depression”). But a person with bipolar disorder also experiences extreme high – euphoric or irritable – moods called “mania” or a less severe form called “hypomania.”

Sign and Symptoms of depression-
(1) Persistent sad, anxious, or “empty” mood
(2) Feelings of hopelessness, or pessimism
(3) Irritability, Feelings of guilt, worthlessness, or helplessness
(4) Loss of interest or pleasure in hobbies and activities
(5) Decreased energy or fatigue, moving or talking more slowly
(6) Feeling restless or having trouble sitting still
(7) Difficulty concentrating, remembering, or making decisions
(8) Difficulty sleeping, early-morning awakening, or oversleeping
(9) Appetite and/or weight changes
(10) Thoughts of death or suicide, or suicide attempts

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