Locus Coeruleus - USMLE Step 1 UWorld Questions, Nervous system, Neurology, Neuroanatomy, MBBS, PLAB

Описание: The locus coeruleus is a paired brainstem nucleus located in the posterior rostral pons near the lateral floor of the fourth ventricle and functions as the principal site for norepinephrine synthesis in the brain. It projects to virtually all parts of the central nervous system and helps control mood, arousal (reticular activating system), sleep-wake states, cognition, and autonomic function.

The locus coeruleus functions as the principal site for norepinephrine synthesis in the brain and projects to virtually all parts of the central nervous system. It is involved in the control of mood, arousal (reticular activating system), sleepwake states, cognition, and autonomic function (eg, blood pressure control). Abnormal activation of the locus coeruleus has been implicated in the pathogenesis of anxiety disorders (eg, panic attacks).

Patients with bilateral pontine hemorrhage typically present with coma due to disruption of the reticular activating system. Other features usually include total paralysis with extensor posturing due to corticospinal and corticobulbar tract injury and pinpoint pupils secondary to descending sympathetic tract damage.

Oxytocin and vasopressin (antidiuretic hormone) are hormones produced by the hypothalamus and released from the posterior pituitary. Oxytocin promotes milk letdown and uterine contractions, whereas vasopressin causes vasoconstriction and free water reabsorption in the renal collecting ducts.

By Image:Brain human sagittal section.svg by Patrick J. Lynch; Image:Brain bulbar region.PNG by DO11.10; present image by Fvasconcellos. - Image:Brain human sagittal section.svg by Patrick J. Lynch, modified to match Image:Brain bulbar region.PNG by DO11.10., CC BY 2.5, https://commons.wikimedia.org/w/index.php?...

By Images are generated by Life Science Databases(LSDB). - from Anatomography[1] website maintained by Life Science Databases(LSDB).You can get this image through URL below. 次のアドレスからこのファイルで使用している画像を取得できますURL., CC BY-SA 2.1 jp, https://commons.wikimedia.org/w/index.php?...

By BodyParts3D by DBCLS. - Polygon data from BodyParts3D by DBCLS, CC BY-SA 2.1 jp, https://commons.wikimedia.org/w/index.php?...

By Ben Mills - Own work, Public Domain, https://commons.wikimedia.org/w/index.php?...

By BruceBlaus - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?...

By OpenStax - https://cnx.org/contents/[email protected]:fEI..., CC BY 4.0, https://commons.wikimedia.org/w/index.php?...

By OpenStax College - Anatomy & Physiology, Connexions Web site. http://cnx.org/content/col11496/1.6/, Jun 19, 2013., CC BY 3.0, https://commons.wikimedia.org/w/index.php?...

By Hariadhi - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?...

Follow Sappheiros
Spotify: https://open.spotify.com/artist/5ZVHX...
Apple Music: / sappheiros
Soundcloud: / sappheirosmusic
Bandcamp: https://sappheiros.bandcamp.com/
Instagram: / sappheirosmusic