“Kiddo’s Tiny Musical KX™️” - Ep 36 - The Perfect Pitch Gene (3)

Описание: “Kiddo’s Tiny Musical KX™️” - Ep 36 - The Perfect Pitch Gene (3)
Date: (M) 01.26.2026
Posted on YouTube: (TH) 01.29.2026
Written by: Jenna Chou, PMP

Location and Gene Context
• rs3057 is a single-nucleotide polymorphism (SNP) — a tiny genetic variant at one position in the DNA sequence.
• In at least one genetic study, rs3057 was identified in a linkage scan on chromosome 8 at band 8q24.21 when researchers looked for regions associated with absolute pitch in families. That region was reported as a peak marker in that study’s analysis.

📍 What gene is it near?

There isn’t one universally accepted “gene for rs3057,” because SNPs can be inside genes, near them, or in non-coding DNA. But here’s what research suggests:
• Some researchers noted that rs3057 is near the ADCY8 gene, which encodes adenylate cyclase 8, a protein that’s expressed in the brain and thought to have roles in cognitive processes. However, the SNP is not inside the main coding part of ADCY8, and the physical distance between rs3057 and ADCY8 is quite large (~462 kilobases, which is far on the DNA scale).
• Other work describes rs3057 as being within an intronic (non-coding) region of the ASAP1 gene. ASAP1 encodes a protein involved in cellular processes like neuronal plasticity.

🧠 Does this mean rs3057 changes those genes?

Not necessarily. Being near or within a gene in a big region doesn’t mean it affects that gene’s function directly. Many SNPs are in non-coding portions of DNA and might influence regulation (how strongly a gene is turned on) rather than changing the protein’s sequence. For rs3057, its functional effects — if any — are not well-understood yet.

🧠 Summary
• rs3057 is a SNP, not a gene.
• It was found in a genomic region (8q24.21) linked to absolute pitch in one study.
• It appears near the ADCY8 gene and within the intron of ASAP1 in the broader DNA region.
• However, no clear functional effect or simple gene-trait cause has been established for this SNP.

Did ChatGPT “Hallucinate” Again?

rs3057 is not a gene and not a “perfect pitch gene.”

It’s just a DNA marker (a SNP) that showed up in one study in a region of chromosome 8 when researchers were looking for links to absolute (perfect) pitch.

Perfect pitch doesn’t come from one gene.
It comes from:
• many small genetic influences (hearing accuracy, brain plasticity, timing),
• plus early musical exposure, especially in childhood.

Summary
• rs3057 is a SNP, not a gene.
• It was found in a genomic region (8q24.21) linked to absolute pitch in one study.
• It appears near the ADCY8 gene and within the intron of ASAP1 in the broader DNA region.
• However, no clear functional effect or simple gene-trait cause has been established for this SNP.

So if you ever see rs3057 mentioned online as “the perfect pitch gene,” that’s an oversimplification bordering on misinformation.

Source:
Jenna Chou, PMP
Google
ChatGPT (“Hallucinated” partially)