Digoxin (Digitalis) Mechanism of Action | Heart Failure Pharmacology | MedLive by Dr Priyanka

Описание: Heart Failure Drugs Explained: MOA of Key Classes | MedLive Pharmacology | Dr Priyanka

Navigating the complex world of Heart Failure medications? 🤔 Let's simplify it! Understand the Mechanism of Action (MOA) of the major drug classes used to treat Heart Failure.
Join Dr. Priyanka Sachdev for a comprehensive overview essential for MBBS students (reflecting current understanding in 2025):
✅ Quick recap: Goals of HF therapy (reduce mortality, morbidity, symptoms).
✅ RAAS Inhibitors: How ACEi (-prils), ARBs (-sartans), and ARNIs (Sacubitril/Valsartan) combat neurohormonal activation. MOA focus!
✅ Beta-Blockers: Why specific agents (Metoprolol Succinate, Carvedilol, Bisoprolol) are crucial & their MOA in blocking sympathetic overactivity.
✅ Diuretics:
Loop Diuretics (e.g., Furosemide): MOA for rapid symptom relief (preload reduction).
Aldosterone Antagonists (Spironolactone/Eplerenone): MOA beyond diuresis (anti-fibrotic, anti-remodeling effects).


✅ SGLT2 Inhibitors (-gliflozins): The newer players! Understanding their MOA in Heart Failure (it's more than just glucose!).
✅ Vasodilators (Hydralazine/Nitrates): MOA in reducing preload and afterload.


✅ Positive Inotropes (like Digoxin): Quick MOA recap (or link to dedicated video).
✅ Understanding why each class helps manage Heart Failure symptoms and progression.
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