Roche’s New GLP-1 Hits 22% Weight Loss! Can it beat Zepbound?

Описание: On this episode of The Downsized News, Christopher and Laraine Durham break down the biggest stories shaping the GLP-1 landscape and what they mean for real people managing obesity and metabolic health.

This week’s show looks at why Novo Nordisk spent nearly $500 million on advertising Wegovy and Ozempic in 2025, and how that spending impacts patients who are paying out of pocket. The episode also covers Serena Williams’ Super Bowl commercial with Ro, Hims & Hers’ push for broader access, and new clinical data on Roche’s next-generation obesity drug showing more than 22% weight loss.

Viewers will also hear about promising research on GLP-1s and eye health, new survey data showing how rising costs are driving risky dosing behavior, and updated findings on post–GLP-1 weight maintenance from Fractyl Health.

As always, Christopher and Laraine bring patient-centered context, clear explanations, and practical insight from their own experience—having lost more than 150 pounds together using GLP-1 therapy. The episode includes sponsor support from Hume Body Pod and reminders about safe, informed use of prescription medications.

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00:00 Roche’s New GLP-1 Hits 22% Weight Loss! Can it beat Zepbound?
01:55 Novo vs. Lilly: The $500 Million GLP-1 Advertising War
06:07 Serena Williams Stars in Ro’s First Super Bowl GLP-1 Ad
08:48 Hims & Hers’ Super Bowl Ad Takes on GLP-1 Access and Inequality
12:42 Roche’s New Obesity Drug vs. Zepbound: How Do They Compare?
16:10 Fractyl’s Revita Shows Promise for Post–GLP-1 Weight Maintenance
20:12 New Study: Can GLP-1s Help Protect Vision in Diabetes?
22:46 Nearly Half of Users Are Cutting GLP-1 Doses to Save Money