Further findings from a Phase I trial of CAR-T in MS: patient-reported outcomes
Автор: VJNeurology
Загружено: 2025-10-30
Просмотров: 313
Описание:
Jeffrey Dunn, MD, Stanford University School of Medicine, Palo Alto, CA, shares insights into the patient-reported outcomes of CAR T-cell therapy in multiple sclerosis (MS) from a Phase I trial (NCT06138132). He discusses that patients were discharged after the infusion of CAR-T therapy, after which they experienced malaise. After about three months, patients reported significant improvements in fatigue levels. These findings highlight the potential clinical activity of CAR-T therapy, but Prof. Dunn emphasizes that they must be replicated and validated in larger cohorts. This interview took place at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Barcelona, Spain.
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