Magnesium in Critical Illness | Metabolism, Biochemistry & Causes of Depletion | Dr. Shrithika Patil

Описание: Magnesium in Critical Illness | Metabolism, Biochemistry & Causes of Depletion | Dr. Shrithika Patil

Understand magnesium metabolism, biochemistry, and why hypomagnesemia is so common in critically ill patients in this concept-driven session by Dr. Shrithika Patil.

This talk explains why serum magnesium often underestimates total body deficiency, how magnesium regulates ATP, enzymatic reactions, neuromuscular function, cardiac stability, bone metabolism, and electrolyte balance, and why low magnesium is associated with arrhythmias, seizures, refractory hypokalemia, hypocalcemia, and increased mortality in ICU patients.

Designed for Emergency Medicine, Critical Care, Internal Medicine residents, and medical students, this session bridges basic physiology with bedside relevance.

Key Topics Covered:

• Total body magnesium distribution & why serum levels are misleading
• Intestinal absorption and renal handling of magnesium
• Role of magnesium in ATP stabilization & enzyme activity
• Magnesium in DNA/RNA synthesis & cellular metabolism
• Bone–magnesium exchange and skeletal health
• NMDA receptor modulation & neuromuscular excitability
• Relationship between magnesium, potassium & calcium
• Why hypokalemia and hypocalcemia don’t correct without magnesium
• Causes of hypomagnesemia in critical illness
• GI losses, renal wasting, drugs & redistribution syndromes
• Hypomagnesemia in sepsis, trauma, burns & DKA
• Clinical manifestations: arrhythmias, seizures, weakness, delirium
• IV vs oral magnesium replacement – indications & dosing principles

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⚠️ Disclaimer: This video is intended for educational purposes only. Clinical decisions should follow institutional protocols, current guidelines, and individual patient assessment.