YIA winner: High intensity interval and traditional endurance training... - Shepard, S.

Описание: [http://www.sport-science.org]

18th annual ECSS Congress Barcelona/Spain, June 26-29 2013

High intensity interval and traditional endurance training both increase insulin sensitivity, VO2peak and skeletal
muscle perilipin 2 and perilipin 5 content in sedentary obese males
Shepherd, S.1, Cocks, M.1, Ranasinghe, A.2, Barker, T.2, McClean, A.2, Wagenmakers, A.J.M.1, Shaw, C.S.3
1: Liverpool John Moores University [Liverpool, UK], 2: University of Birmingham [Birmingham, UK], 3: Victoria University
[Melbourne, Australia]

Introduction: We have recently demonstrated that both sprint interval training [SIT] and traditional endurance-based training [ET]
increase skeletal muscle oxidative capacity, intramuscular triglyceride [IMTG] concentration, VO2peak and whole-body insulin
sensitivity in previously sedentary lean men. We also provided evidence that increases in perilipin 2 [PLIN2] and perilipin 5 [PLIN5]
observed after both training modes played a role in the increased net IMTG breakdown during 1 h of endurance exercise [Shepherd
et al., 2013]. However, SIT requires repeated ‘all-out’ efforts against a very high resistance [Wingate sprints], which may not be
suitable or practical for obese individuals.
Aims: To investigate the hypotheses that in sedentary obese males high intensity interval training [HIT] at a constant load of 200%
Wpeak and ET lead to 1] similar increases in VO2peak and insulin sensitivity and a similar reduction in cardiovascular risk factors;
and 2] similar increases in IMTG, PLIN2 and PLIN5 content.
Methods: Sixteen sedentary obese males [25±2 y, BMI 34.8±1.3 kg.m-2] performed 4 weeks of either HIT [4-7 30s bursts at a
constant load of 200% Wpeak interspersed with 2 min recovery, 3d.wk-1] or ET [40-60 min cycling at ~65% VO2peak, 5d.wk-1].
Values are given as means ± SEM. For analytical methods, statistical methods and power calculation see Shepherd et al. [2013].
Only the main effects of training were significant and are reported.
Results: Training increased VO2peak [HIT 7±3%, ET 12±4; P(smaller)0.05] and the Matsuda insulin sensitivity index [HIT 14±3%, ET 17±9%;
P(smaller)0.05]. Training reduced fasting plasma cholesterol [HIT 13±6%, ET 10±7%; P(smaller)0.05], and fasting plasma triglyceride concentration
[HIT 16±8%, ET 10±7%; P=0.06]. Training increased both PLIN2 [HIT 92±19%, ET 82±23%; P(smaller)0.05] and PLIN5 protein content [HIT]
54±15%, ET 36±10%; P(smaller)0.05] in type I muscle fibres, but a non-significant increase in IMTG concentration [HIT 51±21%, ET
31±25%; P=0.086] was observed.
Conclusions: This study demonstrates that 4 weeks of HIT at 200% Wpeak provides an effective alternative to ET to increase
VO2peak, insulin sensitivity and skeletal muscle PLIN2 and PLIN5 protein content and reduce cardiovascular risk factors in sedentary
obese males. HIT at this high workload appears to be a tolerable and effective alternative to SIT, which is likely too demanding for this
target group.

References: Shepherd SO, Cocks M, Tipton KD, Ranasinghe AM, Barker TD, Burniston JG, Wagenmakers AJM, Shaw CS. [2013]. J
Physiol 591[3]:657-675.

Topic: Biochemistry
Presentation form: Oral
European Database of Sport Science [EDSS]