Impurities- Types & Sources | Pharmaceutical Inorganic Chemistry |B.Pharma. 1st sem |Pharma Hub +

Описание: Hello Guys
Welcome to the channel
I am Krishna Agrahari and in this video I'll be talking about impurities in pharmaceutical substances, its types and various sources from where they arise.

Impurities -
An impurity in pharmaceuticals is defined as any component which is not necessary and can be harmful in the drug substance. In addition, for a drug product, any component that is not a formulation ingredient is considered an impurity.

Impurity is an unwanted entity which can affect the safety, efficacy and purity of the drug substance.

Types of Impurities -
There are three types of impurities in pharmaceutical substances
1. Organic Impurities
2. Inorganic Impurities
3. Residual solvents

Impurities are also classified according to their sources which are
1. impurities associated with APIs
2. impurities that are formed during formulation

Sources of Impurities-:
There are various sources from which the impurities appear in pharmaceutical substances such as
1. Raw materials
2. Intermediates
3. Reagents
4. Catalysts and Solvents
5. Reaction vessels
6. Improper storage
7. Cross contamination
8. Manufacturing errors
9. Packing errors
10. Microbial contamination
11. Chemical instability
12. Storage containers
13. Atmospheric contamination
14. Deliberate adulteration

Appearance of impurities in pharmaceutical substances can be overcome by carefulness and precautions.

Thank you for watching
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