Decoding Drug Mechanism of Action with Chromatin Mapping Assays - Dave Lahr, Foghorn Therapeutics
Автор: EpiCypher
Загружено: 2025-04-09
Просмотров: 268
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Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for combination therapies.
In this GEN webinar, our expert speaker Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, will describe how chromatin mapping assays such as CUT&RUN enable precise investigation of transcriptional mechanisms in drug discovery. You will learn how high-resolution epigenomic tools, including EpiCypher’s CUTANA™ platform, can provide actionable insights into drug-induced changes in transcription factor binding and chromatin structure. You’ll also hear about specific case studies that illustrate how these approaches are used to define MOA and accelerate the development of therapies like targeted protein degraders and enzyme inhibitors.
#drugdiscovery #mechanismofaction #chromatin #epigenome #epigenetics
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