Why Is Accurate Gene Targeting So Difficult To Achieve? - Moments That Shocked Us

Описание: Why Is Accurate Gene Targeting So Difficult To Achieve? Have you ever wondered why making precise changes to genes is so challenging? In this informative video, we'll explain the main obstacles scientists face when trying to edit genes accurately. We'll start by discussing how gene editing tools like CRISPR-Cas9 work and the issues that can arise from off-target effects. You'll learn about the different ways cells repair their DNA after it’s been cut and why this makes achieving perfect edits difficult. We’ll also cover the challenges of delivering gene-editing components into specific cells within the body, especially across barriers like the blood-brain barrier. Additionally, we'll explore how the immune system can react against these tools, potentially reducing their effectiveness. We'll introduce recent innovations such as base editing and prime editing, which aim to make gene targeting safer and more precise without causing double-strand breaks. This video will provide a clear overview of the ongoing efforts to improve gene editing technology and the hurdles that still need to be overcome. Whether you're interested in medical research or the future of genetic therapies, understanding these challenges is essential. Join us for this detailed discussion, and subscribe to our channel for more insights into advances in science and medicine.

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