SGD On Clinical Pharmacology in OBGYN: Fibroids, PCOS, Ovulation Induction & Steroids | MBBS

Описание: This lecture provides a comprehensive review of the medications used in modern Obstetrics and Gynecology, focusing on their mechanisms of action, dosages, and evidence-based protocols.

From managing heavy menstrual bleeding in fibroids to the nuances of steroid coverage for pre-term labor, this video is a high-yield resource for medical students and clinicians.

Key Topics & Clinical Indications:

Heavy Menstrual Bleeding (HMB): First-line medical management using COCPs, Mirena, and the non-hormonal action of Tranexamic Acid [00:01].

Uterine Fibroids: * Second-line therapy with GnRH Agonists (Leuprolide, Goserelin) and the "Flare Effect" [05:25].

Modern alternatives: GnRH Antagonists (Elagolix, Relugolix) and SPRMs like Ulipristal Acetate [09:45].

Role of Mifepristone (RU486) in reducing fibroid size [13:51].

Infertility & Ovulation Induction: * Clomiphene Citrate: Mechanism as a SERM and its side effects [16:23].

Letrozole: Why it is the drug of choice for PCOS patients [20:54].

Obstetric Emergencies & Steroids: * Betamethasone vs. Dexamethasone: Government of India (GOI) protocols and the 24mg total dose for fetal lung maturation [24:32].

Benefits of Steroid Coverage: Reducing Fetal Mortality, IVH, NEC, and RDS [30:30].

Contraindications: Why we avoid steroids in cases of Chorioamnionitis [31:26].


SANTINIKETAN MEDICAL COLLEGE & HOSPITAL
Real Classroom Demonstration/Lecture
On: OBSTETRICS & GYNAECOLOGY by Dr. Inisha Sarkar
(MBBS Batch: 2023-24)
Conducted on: 13-01-25