Why Do Repeated Miscarriages Happen? Complete Women Guide | With Dr Hira

Описание: In a clinical context, Recurrent Pregnancy Loss (RPL) is defined as a distinct disease state characterized by two or more failed clinical pregnancies. It affects approximately 1\% to 2\% of women of reproductive age.

Unlike a sporadic miscarriage, which is often a "one-off" event due to random chromosomal errors, repeated losses often prompt a systematic medical investigation to identify underlying maternal, paternal, or embryonic factors.

Primary Etiologies (Causes)
Medical professionals categorize the causes of repeated miscarriage into several key pillars:

1. Genetic Abnormalities
Aneuploidy: While common in single miscarriages, recurring genetic errors can occur.

Parental Chromosomal Rearrangements: In about 3\% to 5\% of couples experiencing RPL, one partner carries a balanced translocation. While the parent is healthy, the egg or sperm can end up with too much or too little genetic material (unbalanced).

2. Anatomical Factors
Structural issues in the uterus can prevent a pregnancy from developing properly:

Septate Uterus: A congenital condition where a band of tissue divides the uterus.
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Asherman’s Syndrome: Intrauterine scarring, often from previous surgeries.

Fibroids or Polyps: Depending on their location, these can interfere with embryo implantation or blood supply.

3. Endocrine (Hormonal) Disorders
Hormonal health is critical for maintaining the early stages of pregnancy:

Thyroid Dysfunction: Both hypothyroidism and hyperthyroidism are linked to loss.

Luteal Phase Deficiency: Insufficient progesterone production, which is necessary to support the uterine lining.
Uncontrolled Diabetes: High blood glucose levels during conception and early development increase risk.