The Secret Behind a Strange Stimulant
Автор: That Chemist
Загружено: 2022-09-04
Просмотров: 150597
Описание:
This is an investigation into why 8-chlorotheophylline is present as a stimulant in Gravol anti-nausea medication. A huge thanks to tay and yuyuhakase from the Discord!
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References:
1st patent - https://patents.google.com/patent/US2...
2nd patent - https://patents.google.com/patent/US2...
1st science paper - https://www.doi.org/10.1126/science.1...
2nd science paper - https://www.doi.org/10.1126/science.1...
anti-nausea discovery - https://www.doi.org/10.1126/science.1...
Predicted pKa sources:
8-chlorotheophyline - https://www.chemicalbook.com/ProductC...
theophylline - https://pubchem.ncbi.nlm.nih.gov/comp...
diphenhydramine - https://pubchem.ncbi.nlm.nih.gov/comp...
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