Liposomes - Six Decades On: The Old Kid On The Cancer Nanomedicine Block
Автор: NMIN NCE
Загружено: 2022-04-20
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A Pieter Cullis Invitational Lecture with Dr. Francis Szoka
As we approach the sixtieth anniversary of the first description of a liposome by Alec Bangham, Dr. Szoka briefly reflects upon the reasons for the successes of liposome encapsulated drugs in cancer drug therapy. More relevant to the future, as many others have pointed out, we need to comprehend why liposomes haven’t been more successful clinically and what this implies for the broader research area of nanomedicines.
This presentation focuses on relevant results from Dr. Szoka's group in three areas: drug encapsulation and release, long circulation, and tissue and tumor penetration. According to Dr. Szoka, there remain challenging, unresolved research opportunities for curious scientists to understand and exploit for improved cancer nanomedicine delivery.
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